Jothy Rosenberg, a successful entrepreneur with 35 years of experience founding and running startups, shares his insights on why 7.5 out of 10 venture-backed startups fail. He believes that it's because the founders lack focus on five crucial aspects: having the right CEO, proving product-market fit, raising money from the right investors, managing runway, and fostering a strong company culture. He emphasizes that during the initial phase, the CEO should be the person with the strongest passion and ability to articulate the solution, rather than solely relying on sales and marketing expertise. Additionally, Rosenberg stresses the importance of identifying a narrowly defined market segment, finding lighthouse customers to define the minimum viable product, and continuously testing and improving to prove product-market fit.